STATINS OF NO BENEFIT AGE 80 AND UP, even after a heart attack!

Finally IT HAS BEEN LOOKED AT AND TRUTHFULLY PUBLISHED, statin drugs for individuals 80 years of age and older  WITH DOCUMENTED HEART DISEASE SHOWS NO BENEFIT, EVEN AFTER A HEART ATTACK

Here is the abstract from the study

Statin Therapy and Mortality in Older Adults With CAD
Abstract
Objectives: To examine the effect of statins on long-term mortality in older adults hospitalized with coronary artery disease (CAD).
Design: Retrospective analysis.
Setting: University teaching hospital.
Participants: Individuals aged 80 and older (mean aged 85.2, 56% female) hospitalized from January 2006 to December 2010 with acute myocardial infarction (AMI), unstable angina pectoris, or chronic CAD and discharged alive (N = 1,262). Participants were divided into those who did (n = 913) and did not (n = 349) receive a discharge prescription for a statin.
Measurements: All-cause mortality over a median follow-up of 3.1 years.
Results: Participants treated with statins were more likely to be male, to have a primary diagnosis of AMI, to have traditional cardiovascular risk factors, and to receive other standard cardiovascular medications in addition to statins. In unadjusted analysis, statin therapy was associated with lower mortality (hazard ratio (HR) = 0.83, 95% confidence interval (CI) = 0.71–0.96). After adjustment for baseline differences between groups and propensity for receiving statin therapy, the effect of statins on mortality was no longer significant (HR = 0.88, 95% CI = 0.74–1.05). The association between statins and mortality was similar in participants aged 80 to 84 and those aged 85 and older.
Conclusion: In this cohort of older adults hospitalized with CAD, statin therapy had no significant effect on long-term survival after adjustment for between-group differences. These findings, although preliminary, call into question the benefit of statin therapy for secondary prevention in a real-world population of adults aged 80 and older and underscore the need for shared decision-making when prescribing statins in this age group.

In layman’s terms. This study compared patients aged 80 and older who were hospitalized with documented coronary artery disease and compared those sent home on statins and those sent home without a prescription for statins. There was no difference in death rates between the two groups. The use of statins in this situation (known heart disease) is referred to as secondary prophylaxis. Secondary prophylaxis would be expected to have greater risk reduction when compared to primary prophylaxis (no know heart disease).

I have advocated against the use of statins in primary prophylaxis. Statin Guidelines, one step forward, two steps backwards | Practical Evolutionary Health

The data in this study shows no protection from statins when used for secondary prophylaxis (higher risk group) for age 80 and above.

For more discussions on statins, atherosclerosis, coronary artery disease, go here. Statin Drugs | Practical Evolutionary Health

Live clean, eat clean, sleep well.

Bob Hansen MD

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